Julia Roberts as Barbara Weston

Meryl Streep as Violet Weston

Julianne Nicholson as Ivy Weston

Juliette Lewis as Karen Weston

Ewan McGregor as Bill Fordham

Margo Martindale as Mattie Fae Aiken

Abigail Breslin as Jean Fordham

Chris Cooper as Charlie Aiken

Dermot Mulroney as Steve Huberbrecht

Benedict Cumberbatch as Little Charles Aiken

Misty Upham as Johnna Monevata

Sam Shepard as Beverly Weston

Will Coffey as Sheriff Deon Gilbeau

Newell Alexander as Dr. Burke

Jerry Stahl as Liquor Store Owner

Dale Dye as Radio Announcer

Ivan Allen as Radio Announcer

Arlin Miller as Baseball Announcer

J. Alan Davidson as Young Soldier (uncredited)

Michael Graham as Restaurant Patron (uncredited)

Maria Gus as Funeral Attendee (uncredited)

Leland Prater as Funeral Attendee (uncredited)