Darren McGavin as Carl Kolchak

Carol Lynley as Gail Foster

Simon Oakland as Tony Vincenzo

Ralph Meeker as Bernie Jenks

Claude Akins as Sheriff Warren A. Butcher

Charles McGraw as Police Chief Ed Masterson

Kent Smith as District Attorney Tom Paine

Elisha Cook Jr. as Mickey Crawford

Stanley Adams as Fred Hurley

Larry Linville as Dr. Robert Makurji

Jordan Rhodes as Dr. John O'Brien

Barry Atwater as Janos Skorzeny

Edward Faulkner as Las Vegas Policeman (uncredited)

Virginia Gregg as Mrs. Brandon (uncredited)

Buddy Joe Hooker as Intern (uncredited)

Irene Cagen as

Edward Faulkner as

Sig Frohlich as

Eddie Garrett as

Virginia Gregg as

Buddy Joe Hooker as

Monty O'Grady as

Peggy Rea as

Mark Russell as

George Simmons as