Tara Strong as Ben Tenyson (voice)

Meagan Moore as Gwen Tennyson (voice)

Paul Eiding as Grandpa Max (voice)

Richard McGonagle as Four Arms (voice)

Robert David Hall as Azmuth (voice)

Fred Tatasciore as Cannonbolt / Way Big (voice)

Vanessa Marshall as Myaxx / Salesperson (voice)

Dwight Schultz as Dr. Animo (voice)

Steve Blum as Vilgax / Heatblast / Nightmarish Alien / Alien Fly Prisoner (voice)

Jim Ward as XLR8 / Ripjaws Prisoner / Incarcecon Security (voice)

Dee Bradley Baker as Robotic Lt / Wildmutt / Gluto / Eye Guy / Alien Prisoner #1 / Automated Security (voice)

Richard Steven Horvitz as Grey Matter / Stinkfly Prisoner (voice)

Dave Wittenberg as Upchuck / Alien #2 (voice)

Dave Fennoy as Tetrax / Alien #1 / Alien Prisoner #2 (voice)