Frank Welker as Garfield / Garzooka / Narrator (voice)

Vanessa Marshall as Vetvix (voice)

Gregg Berger as Odie / Odious (voice)

Wally Wingert as Jon Arbuckle / Emperor Jon (voice)

Audrey Wasilewski as Arlene / Starlena (voice)

Jason Marsden as Nermal / Abnermal (voice)

Fred Tatasciore as Billy Bear / Horned Guard (voice)

Stephen Stanton as Randy Rabbit / News Guy / Skinny Guard (voice)

Jennifer Darling as Betty / Bonita (voice)

Neil Ross as Wally / Professor Wally / Charles (voice)

Greg Eagles as Eli (voice)

Cathy Cavadini as Additional Voices (voice)

Paige Pollack as Additional Voices (voice)

David Michie as Additional Voices (voice)

Greg Finley as Additional Voices (voice)

Ruth Zalduondo as Additional Voices (voice)

Jeff Fischer as Additional Voices (voice)