Rodney Dangerfield as Thornton Melon

Sally Kellerman as Diane

Burt Young as Lou

Keith Gordon as Jason Melon

Robert Downey Jr. as Derek

William Zabka as Chas

Paxton Whitehead as Phillip Barbay

Adrienne Barbeau as Vanessa

M. Emmet Walsh as Coach Turnbull

Terry Farrell as Valerie

Ned Beatty as Dean Martin

Severn Darden as Dr. Barazini

Sam Kinison as Professor Terguson

Robert Picardo as Giorgio

Kurt Vonnegut as Self

Edie McClurg as Marge

Sarah Abrell as Sorority Girl

Dana Allison as Young Woman

Boris Aplon as Tony Meloni

Nora Boland as Agnes

Kimberlin Brown as Girl in Dorm Hallway

Lisa Denton as Lisa

Bob Drew as Contractor

Holly Hayes as Girl in the Crowd

Jason Hervey as Young Thornton

Leslie Scarborough as Coed #1

James Ingersoll as Judge

Michael McGrady as Player #1

Santos Morales as Bartender

Beth Peters as Mrs. Stuyvesant

Phil Rubenstein as Executive #1

Timothy Stack as Trendy Man

Steve Sweeney as Security Guard

Stacey Toten as Hot Tub Girl

John William Young as Executive #2

Brad Zutaut as Petey

Josh Saylor as Student in Diane's Class

William Grauer as Drunken Student

Kristen Aldrich as Girl in Diane's Class

Becky LeBeau as Hot Tub Girl

Tricia Hill as Lisa's Friend

Jill D. Merin as Girl at Dorm Party

John William James as Man in Stands

Eric Alver as Student at Fraternity Party

Theresa Lyons as Cashier

Dallas Winkler as Rodette

Lisa Montgomery as Rodette

Kimberlee Carlson as Rodette

Curtis Stone as "Twist & Shout" Band Member

Michael Reid as "Twist & Shout" Band Member

Cactus Moser as "Twist & Shout" Band Member

Brian O'Doughtery as "Twist & Shout" Band Member

Davey Faragher as "Twist & Shout" Band Member

Cliffie Stone as "Twist & Shout" Band Member

Danny Elfman as Oingo Boingo Band Member

Leon Schneiderman as Oingo Boingo Band Member

Steve Bartek as Oingo Boingo Band Member

Dale Turner as Oingo Boingo Band Member

Johnny Vatos Hernandez as Oingo Boingo Band Member

John Avila as Oingo Boingo Band Member

Sam 'Sluggo' Phipps as Oingo Boingo Band Member

Mike Bacich as Oingo Boingo Band Member