Nick Robinson as Joe Toy

Gabriel Basso as Patrick Keenan

Moisés Arias as Biaggio

Nick Offerman as Frank Toy

Erin Moriarty as Kelly

Craig Cackowski as Mr. Larson

Alison Brie as Heather Toy

Megan Mullally as Mrs. Keenan

Marc Evan Jackson as Mr. Keenan

William Sonnie as Track Suit

Nathan Keyes as Paul

Cristoffer Carter as Construction Kid

Priscilla Kaczuk as Grandma Keenan

Eugene Cordero as Colin

Gillian Vigman as Carol

Mary Lynn Rajskub as Captain Davis

Thomas Middleditch as Rookie Cop

Lili Reinhart as Vicki

Austin Abrams as Aaron

Paul Floriano as Italian Man

Brian Sacca as No Sideburns

Peter Karinen as No Sideburns' Friend

Tony Hale as Bus Passenger

Hannibal Buress as Bus Driver

Kumail Nanjiani as Gary

Jeffrey Grover as Detective

Eric Wasserman as Second Detective

Nick Rutherford as Visor

Angela Trimbur as Face Paint

Jennifer Lindgren as News Reporter

Michael Cipiti as Biaggio's Dad

Kim Bordwine as Nurse (uncredited)

Christina Cacic as High School Teacher (uncredited)

Justin Cooney as Teen / Beach Party (uncredited)

Anthony Daniel as High School Student (uncredited)

Eric Frank as Doctor (uncredited)

Logan Fry as Hospital Patient in Wheelchair (uncredited)

Joe Gallipoli as Doctor (uncredited)

David Gragg as Doctor (uncredited)

Hannah Harris as Parade Spectator (uncredited)

Linda Marie Howell as Doctor in Plain Clothes (uncredited)

Christopher Kaczmarek as Boston Market Employee (uncredited)

Cole Kornell as Track Suit Friend (uncredited)

Maria Laskowski as High School Student (uncredited)

Daniel T. Martin as Detective (uncredited)

Derick Mayes as Nurse (uncredited)

Christine McBurney as Bus Passenger (uncredited)

Shawn Michelle as Bus Passenger (uncredited)

Tyler Moliterno as Big Italian Kid (uncredited)

Taylor Nelms as High School Student (uncredited)

Brady Novak as Deli Owner (uncredited)

David Sanborn as High School Student (uncredited)

Julie Simon as Teacher (uncredited)

Joel Thingvall as High School Principal (uncredited)

Josh Tippey as Paul's Friend (uncredited)

Nicole Tubbs as Doctor (uncredited)

Lisa Y. Wong as Doctor (uncredited)

Abigail Wylie as High School Student (uncredited)

Theresa Wylie as Doctor (uncredited)