Mark Burnham as Officer Duke

Steve Little as Officer Sunshine

Eric Judor as Officer Rough

Marilyn Manson as David Dolores Frank

Arden Myrin as Officer Holmes

Eric Wareheim as Officer de Luca

Grace Zabriskie as Donna (Duke's mother)

Eric Roberts as Bob

Izzy Palmieri as Rose

Ray Wise as Captain Andy

Jennifer Blanc as Ruth (Rough's neighbor)

Daniel Quinn as Neighbor

Hillary Tuck as Kylie (Sunshine's wife)

Don Stark as Gary

Tim Trobec as André (Ruth's husband)

Joel Bryant as Bill (Holmes' husband)

Roxane Mesquida as Girl

Kurt Fuller as Music Producer

Mary Loveless as Cashier

Flying Lotus as Customer

Steve Howey as Sandy / Michael

Agnes Bruckner as Julia Kieffer

Brandon Beemer as Officer Brown

Jon Lajoie as Officer Regan

Bob McCracken as Willy

Jack Plotnick as Special Guest

Ping Wu as Chinese

Brennan Feonix as Screw

Norton Leufven as Kid (in Diner)

Alyssa Preston as Cynthia

Mona Walravens as Special Guest

Pete Cross as Father (uncredited)

Sebastian Feldman as Crying Cop at Funeral (uncredited)

Annmarie Lynn Gracey as Trashy Girlfriend (uncredited)

Nicky Hawthorne as Julia's Griend (uncredited)

Jen Nikolaisen as Sally (Stroller Mom) (uncredited)