Marc Anthony as Hector Lavoe

Jennifer Lopez as Puchi

John Ortiz as Willie Colon

Manny Perez as Eddie

Vincent Laresca as Ralph

Federico Castelluccio as Jerry Masucci

Nelson Vasquez as Johnny Pacheco

Antone Pagán as Papo

Romi Dias as Priscilla

Jared Everleth as Tito (4 yrs.)

Bernard Hernandez as Tito (7 yrs.)

Christopher Becerra as Tito (12-15 yrs.)

Andrea Navedo as Zaida

Ismael Miranda as Hector's Father

Tito Allen as Singer

Víctor Manuelle as Ruben Blades

Michael Wright as Shooting Gallery Man

Cucu Diamantes as Female Junkie

Marina Durell as Madrina

Guillermo de Cun as Priest

Jack Mulcahy as Doctor

Israel Sanabria as M.C.

Joe Lala as Band Leader

Domingo Quiñones as San Juan Promoter

Elliot Santiago as Bouncer

Obie Bermúdez as Taxi Driver

Glenda Dopazo as Carmen

Hector A. Leguillow as Pianist

Lou Torres as Pianist 2/Pianist (After hrs.)

Victor Santos as Pianist 3

Hugo Duran as Bassist

Julio Ortiz as Trumpet

Jorge Pupo as Trombone Player

Danny A. Abeckaser as Studio Engineer

Marlon Belcione as Party Goer #1

Arlene Rodriguez as Mercedes

Roberto Romero as Background Singer #3

Eddie Rosado as Chorus

Chiko Mendez as Chorus

Deirdre Lorenz as Willie's Girl

Grant Crawford as Interviewer

Luis Eduardo Santiago Diaz as Paramedic

Edwin Rivera as Cheetah Solo Dancer

Yomo Toro as Self

Eddie Montalvo as Self

David Marquez as Boogaloo Line Dancer

Jerry Perez as Salsa Dancer

Marcus Collins as Photographer (uncredited)

Kaly Cordova as Family Member (uncredited)

Abraham De Funes as Family Member (uncredited)

Wanda Ferreiras as Fania All-Star Groupie (uncredited)

Luis Galli as Friend in the bar (uncredited)

Rodyniel Gonzalez as Dancer in the audience concert (uncredited)

Hristo Hristov as Photographer (uncredited)

Ana Isabelle as Puchi's Friend (uncredited)

Amerindia Laz as Salsa Dancer (uncredited)

Pierangeli Llinas as Salsa Dancer (uncredited)

Claudia Lopez as Party goer - Puchi's birthday party (uncredited)

Desiree Ortiz as Boom Operator (uncredited)

Gloria Parks as Salsa Dancer (uncredited)

Martha Peralta as Dancer #1 (uncredited)

Robert Resto as Dancer (uncredited)

Jimmy Santos as Dancer (uncredited)

Charles Santy as Bartender (uncredited)

Richard Vallejos as Roadie (uncredited)