Alec Baldwin as Mr. Conductor

Peter Fonda as Grandpa Burnett Stone

Mara Wilson as Lily Stone

Eddie Glenn as Thomas (voice)

Neil Crone as Diesel 10 / Gordon / Splatter / Tumbleweed (voice)

Michael E. Rodgers as Mr. C. Junior

Britt Allcroft as Lady (voice)

Kevin Frank as Henry / Dodge / Bertie / Harold (voice)

Linda Ballantyne as Percy (voice)

Susan Roman as James (voice)

Colm Feore as Toby (voice)

Cody McMains as Patch

Didi Conn as Stacy Jones

Russell Means as Billy Twofeathers

Lori Hallier as Lily's Mother

Shelley-Elizabeth Skinner as Annie / Clarabel (voice)

Jared Wall as Young Bernett (voice)

Laura Bower as Young Tasha (voice)

Doug Lennox as Motorcyle Passerby (uncredited)

Bentley as Mutt the Dog (uncredited)

Dila as Mutt the Dog (uncredited)