Dustin Hoffman as Harvey Shine

Emma Thompson as Kate Walker

Eileen Atkins as Maggie Walker

Kathy Baker as Jean

Liane Balaban as Susan Shine Wright

Daniel Lapaine as Scott Wright

James Brolin as Brian

Richard Schiff as Marvin

Wendy Mae Brown as Aggie

Bronagh Gallagher as Oonagh

Jeremy Sheffield as Matt

Patrick Baladi as Simon

Adam James as Josh Hillman

Michael Landes as Peter Turner

Jamie Sives as Doctor Butler

Angela Griffin as Melissa

Charlotte Lucas as Gwen

Gaia Wise as Girl at Wedding

Imogen Byron as Niece at Wedding

Ginny Holder as Nurse

Mickey Sumner as Friend of the Bride

Tolula Adeyemi as Monique the Jazz Singer

Jemma Bolt as Sarah

Robert Jezek as Polish Neighbor

Leslie Randall as Mild Mannered Mike

Adam Astill as Businessman

Tim Howar as Johnnie

Kate Harper as Jill

Alex Avery as Andrew

Tim Ahern as Barry

Nadia Cameron-Blakey as Attractive Woman

Heather Bleasdale as Receptionist

Femi Oguns as Room Service Waiter

Noah Marullo as Silent Boy

Pascal Scott as Paddy the Postman

Rene Costa as Airport Passenger (uncredited)