Michael Keaton as Johnny Dangerously

Joe Piscopo as Vermin

Marilu Henner as Lil

Maureen Stapleton as Mom

Peter Boyle as Dundee

Griffin Dunne as Tommy

Glynnis O'Connor as Sally

Dom DeLuise as The Pope

Richard Dimitri as Maroni

Danny DeVito as Burr

Ron Carey as Pat

Ray Walston as Vendor

Dick Butkus as Arthur

Byron Thames as Young Johnny

Sudie Bond as Cleaning Lady

Alan Hale Jr. as Desk Sergeant

Scott Thomson as Charley

Carl Gottlieb as Dr. Magnus

Neal Israel as Dr. Zillman

Mark Jantzen as Dutch

Hal Riddle as Warden

Mike Bacarella as Vito

Gary Watkins as Manny

Hank Garrett as Mayor

Leonard Termo as Tony Scarano

Troy Slaten as Young Tommy

Alexander Hertzberg as Boy in Suit

Georg Olden as Young Vermin

Cynthia Szigeti as Mrs. Capone

Elizabeth Arlen as Girl on Steps

Doris Grossman as Woman

Richard Warwick as Prisoner

Mike Finneran as Prisoner

Paul B. Brice as Prisoner

Will Seltzer as Prisoner

Dick Balduzzi as Prisoner

Gordon Zimmerman as Prisoner

Katie La Bourdette as Blond Girl

Norman Steinberg as Reporter Duffy

Frank Slaten as Henchman

Dean R. Miller as Photographer

Edward C. Short as Porter

Shelley Pogoda as Woman

Jerome Michaels as Reporter Diering

Russell Forte as Hood

Jack Nance as Priest

Joy Michael as Chorus Girl

Rick Rosenthal as Judge

Paula Dell as Mrs. Zimmer

Harvey Parry as Policeman

Jeffrey Weissman as T-Shirt Vendor

Richard A. Roth as Prisoner Rabbi

Chuck Hicks as Governor

Bob Eubanks as M.C.

Claudia Kim as Girl

Trisha Long as Female Butler

Mert Rich as Man

Vincent Schiavelli as Maroni's Building Planner (uncredited)

Taylor Negron as Delivery Man (uncredited)

Joe Flaherty as Death Row Inmate (uncredited)

Hank Robinson as Policeman (uncredited)

Susan Lanier as Radio Singer (uncredited)

Frank Sivero as Plumber (uncredited)

Tom Willett as Theater Patron (uncredited)