George O'Hanlon as George Jetson (voice)

Mel Blanc as Mr. Spacely (voice)

Penny Singleton as Jane Jetson (voice)

Tiffany as Judy Jetson (voice)

Patric Zimmerman as Elroy Jerson (voice)

Don Messick as Astro (voice)

Jean Vander Pyl as Rosie the Robot (voice)

Brad Garrett as Bertie Ferbelow (voice)

Rick Dees as Rocket Rick Ragnarok (voice)

Frank Welker as Squeep / Grungees (voice)

Ronnie Schell as Rudy 2 (voice)

Patti Deutsch as Lucy 2 (voice)

Dana Hill as Teddy 2 (voice)

Russi Taylor as Fergie Furbelow (voice)

Paul Kreppel as Apollo Blue (voice)