Steven Weber as Jeffrey

Patrick Stewart as Sterling

Michael T. Weiss as Steve Howard

Bryan Batt as Darius

Nathan Lane as Father Dan

Sigourney Weaver as Debra Moorhouse

Olympia Dukakis as Mrs. Marcangelo

Robert Klein as Skip Winkley

Christine Baranski as Ann Marwood Bartle

Kathy Najimy as Acolyte

Debra Monk as Mom

Peter Maloney as Dad

J. Smith-Cameron as Sharon

K. Todd Freeman as Barney's Waiter

Victor Garber as Tim

Ethan Phillips as Dave

Camryn Manheim as Single Woman

Alice Drummond as Grandma Rose

Peter Jacobson as Man #1

David Thornton as Man #3

Irma St. Paule as Mother Teresa

Jeff Ross as Movie Theater Guy

Joe Dain as Movie Theater Guy

Patrick Kerr as Waiter / Actor / Policeman

Peter Bartlett as Casting Director

John Seidman as Boss

Barton Heyman as Elderly Man

Darryl Theirse as Homeboy

Lou Sumrall as Thug #1

Robert Capelli Jr. as Thug #2

Vince Cupone as Thug #3

Nancy Ticotin as Woman in the Window

Gregory Jbara as Angelique

Marylouise Burke as Aunt Phyllis

Sarah Peterson as Nurse

Joe Ponazecki as Uncle Barney

Henry Stram as Cousin Gary

Kevin Nealon as TV Reporter