Mandy Moore as Ava

Kellan Lutz as Charlie

James Brolin as Bradley

Jane Seymour as Betty

Jessica Szohr as Shelby

Michael Weston as Gerber

Marta Żmuda-Trzebiatowska as Kasia

Richard Alan Reid as Ian

Christopher Lloyd as Dr. George

Alexis Denisof as Lloyd

Alyson Hannigan as Courtney

Colleen Camp as Ethel

Julia Roberts as Ava's Therapist (voice)

Andrew Keegan as Jeremiah

Gabrielle Shuff as Adrianna

Autumn Federici as Jessica

Joe Chrest as