Sharlto Copley as Wikus van de Merwe

Jason Cope as Christopher Johnson / Grey Bradnam / Trent

Nathalie Boltt as Sarah Livingstone - Sociologist

Sylvaine Strike as Dr Katrina McKenzie

Elizabeth Mkandawie as Interviewee

John Sumner as Les Feldman - MIL Engineer

William Allen Young as Dirk Michaels

Nick Blake as Francois Moraneu - CIV Engineer Team

Greg Melvill-Smith as Interviewer

Robert Hobbs as Ross Pienaar

Vanessa Haywood as Tania van de Merwe

Morena Busa Sesatsa as Interviewee

Themba Nkosi as Interviewee

Mzwandile Nqoba as Interviewee

Barry Strydom as Interviewee

Jed Brophy as James Hope - Police Officer

Louis Minnaar as Piet Smit

Marian Hooman as Sandra van de Merwe

Vittorio Leonardi as Michael Bloemstein - MNU Alien Civil Affairs

David Clatworthy as MNU Doctor

Michael Huff as MSU Doctor

David James as Koobus Venter

Tim Gordon as Clive Henderson - Entomologist

Anthony Bishop as Paramedic

Anthony Fridjhon as MNU Executive

Eugene Khumbanyiwa as Obesandjo

Melt Sieberhagen as Anton Grobler

Andre Odendaal as Mike Van Kerland

Louise Saint-Claire as MNU Medical Student

Norman Anstey as MNU Lead Medical Technician

Nick Boraine as Craig Weldon

Brandon Auret as MNU Mercenary

Jacques Gombault as MNU Mercenary

Justin Strydom as MNU Mercenary

Simo Mogwaza as MNU Mercenary

Matt Stern as MNU Mercenary

David Dukas as MNU Mercenary

Daniel Hadebe as MNU Guard

Bongo Mbutuma as Nigerian Gangster

Johnny Selema as Nigerian Gangster

Mandla Gaduka as Fundiswa Mhlanga

Johan van Schoor as Nicolas van de Merwe

Stella Steenkamp as Phyllis Sinderson - MNU Alien Relations

Mampho Brescia as Reporter

Morne Erasmus as MNU Medic

Hlengiwe Madlala as Sangoma

Siyabonga Radebe as Obesandjo's Lieutenant

Alan Glauber as MNU Operating Room Doctor

Nicolas Herbstein as MNU Biolab Technician

Sibulele Gcilitshana as Ü Günters Woman

Mahendra Raghunath as SABC Anchor Person

Phillip Mathebula as Meat Stall Seller

Claudine Bennent as MNU Office Worker

Michelle Ayden as MNU Office Worker

Antony Sarak as MNU Office Worker

Billy Somagaca as MNU Office Worker

Ryan Whittal as MNU Office Worker

John Jacob as MNU Office Worker

Yashik Maharaj as MNU Office Worker

Fernando Saraiva as MNU Office Worker

Sharon Waugh as MNU Office Worker

Theunis Nel as MNU Mercenary

Sonni Chidiebere as MNU Mercenary

Danny Datnow as MNU Mercenary

Wisani Mbokota as MNU Guard

Craig Jackson as MNU Guard

Justin Duplessis as MNU Guard

Rodney Downey as MNU Guard

Den Antonakas as MNU Guard

Mashabela Galane as Nigerian Gangster

Mfazwe Sekobane as Nigerian Gangster

Nicholas Ratlou as Nigerian Gangster

Saint Gregory Nwokedi as Nigerian Gangster

Donalson Rabisi as Nigerian Gangster

Zephania Sibanda as Nigerian Gangster

Gideon Thodane as Nigerian Gangster

Mdu Mthabela as Nigerian Gangster

David Mikhethi as Nigerian Gangster

Jeffries Simelane as Nigerian Gangster

Shafique Allan as Nigerian Gangster

Wendy Mbatha as Nigerian Hooker

Leigh Mashupye as Nigerian Hooker

Beauty Setai as Nigerian Hooker

Nkiyase Mondlana as Nigerian Hooker

Kuda Rusike as Soweto Resident

Morena Setatsa as Soweto Resident

Mpho Molao as Soweto Resident

Ntombi Nkuua as Soweto Resident

Absalom Dikane as Soweto Resident

Monthandazo Thomo as Soweto Resident

Norman Thabalala as Soweto Resident

Siphiwe Mbuko as Soweto Resident

Shiela Nene as Soweto Resident

Neill Blomkamp as Man with Wikus' Coordinates (uncredited)

Trevor Coppola as MNU Mercenary (uncredited)

Kenneth Nkosi as Thomas