Jack Lemmon as President Russell P. Kramer

James Garner as President Matt Douglas

Dan Aykroyd as President William Haney

John Heard as Vice President Ted Matthews

Wilford Brimley as Joe Hollis

Lauren Bacall as Margaret Kramer

Sela Ward as Kaye Griffin

Everett McGill as Col. Paul Tanner

Bradley Whitford as Carl Witnaur

James Rebhorn as Charlie Reynolds

Esther Rolle as Rita

Conchata Ferrell as Woman Truck Driver

Jack Kehler as Wayne

Connie Ray as Genny

Tom Everett as NSA Agent Wilkerson

Mark Lowenthal as NSA Agent Caldwell

Jeff Yagher as Dorothy / Lt. Ralph Fleming

Edwin Newman as Edwin Newman - News Anchor

Lynn Clark as Chrissy Kramer

Leigh Rose as Katherine Douglas

Mihoko Tokoro as Japanese Singer

Ken Enomoto as Hiroshi Ashino

Gunnar Peterson as Bruce

Scott Burkholder as Greg

Wayne Duvall as Chet

Jack Garner as President Haney's Caddy

Gene Boland as Injured Golf Spectator

Francesca Rollins as Reporter #1

Paul Feig as Reporter #2

Cathy Ladman as Reynolds' Secretary

Tom Wright as Jim

Dana Gould as Sandwich Guy at Book Convention

Scott Hoxby as Man with Subpoena

Jonathan Osser as Kramer's Grandson

Mitch Braswell as Marine One Pilot

E. Arthur Booth as Marine One Co-Pilot

Steve Carlisle as Man in Train Station Bathroom

Todd McDurmont as Elvis / Francis

Madison Wellington as Tina

David Malloy as Will

Jennifer Leigh Jones as Fran

Rob Roy Fitzgerald as Dean

Jennifer Austin as Marilyn Monroe

Bobby Bass as NSA Hitman #1

Steve Chambers as NSA Hitman #2

Jimmy Nickerson as NSA Hitman #3

Cara Gooden as Truck Stop Girl

Matthew R. Zboyovski as Truck Stop Boy

Michael Peña as Ernesto

Alex Joganic as Kevin

Ocie Pouncie as Man in Diner

Neva Howell as Charlene, Budget Agent

Sheri Mann Stewart as Sandy, Budget Agent

Pete Penuel as Man in Parade

John O'Leary as Ben, Caretaker

Leighanne Littrell as Witnaur's Girlfriend

Rick Hall as U.S. Secret Service Uniformed Division Officer

Eric Siegel as President Haney's Aide

Ann Cusack as White House Tour Guide

Jean Speegle Howard as Asthmatic Woman on Tour

Dorothy Lucey as News Anchor

Jeff Mandon as Secret Service Agent

James D. Bissell as Secret Service Agent

Shawn D. Woodyard as Secret Service Agent

Steve Wedan as Mounted Policeman #1

Tom Sean Foley as Mounted Policeman #2

Michael Russo as White House Sharpshooter

Christopher Kriesa as Agent Kopeck

William Kerr as Vice President Matthews' Make-Up Man

Peter Segal as TV Technician

Jeffrey J. Ayers as Train Station Onlooker (uncredited)

Greg Bronson as Pollster (uncredited)

Tory Christopher as Campaign Aide (uncredited)

Scott Fowler as Bystander (uncredited)

C. Michael Haynes as Policeman (uncredited)

Marg Helgenberger as Joanna (uncredited)

Jan Jackson as Lady in Train (uncredited)

Steph Robinson as Tarheel Fan (uncredited)

Jesse G. Martin as Specialty Performer (uncredited)

Jennifer L. Ray as Funeral Mourner (uncredited)

Robert Shepherd as Restaurant Patron (uncredited)

Sam P. Whitehead as Rude Waiter (uncredited)