Colin Farrell as Stu Shepard

Kiefer Sutherland as The Caller

Forest Whitaker as Captain Ramey

Radha Mitchell as Kelly Shepard

Katie Holmes as Pamela McFadden

Paula Jai Parker as Felicia

Arian Ash as Corky

Tia Texada as Asia

John Enos III as Leon

Richard T. Jones as Sergeant Cole

Keith Nobbs as Adam

Dell Yount as Pizza Guy

James MacDonald as Negotiator

Josh Pais as Mario

Yorgo Constantine as ESU Commander

Colin Patrick Lynch as ESU Technician

Troy Gilbert as ESU Sniper

Seth William Meier as Officer McDuff

Svetlana Efremova as Erica

Billy Erb as Lars

Domenick Lombardozzi as Wyatt

Maile Flanagan as Lana

Tom Reynolds as Richard

Julio Oscar Mechoso as Hispanic Medic

Karara Muhoro as Nigerian Vendor

Zidu Chen as Korean Husband

Shu Lan Tuan as Korean Wife

Dean Cochran as Reporter #1

Amy Kowallis as Reporter #2

Tory Kittles as Reporter #3

Bruce Roberts as Reporter #4

Tyree Michael Simpson as Doorman

Dean Tarrolly as Newscaster

Mary Randle as Dispatcher

Paul Fontana as Dispatcher

Steve Alterman as (voice)

Kimberly Bailey as (voice)

Jason Broad as (voice)

Lanei Chapman as (voice)

Django Craig as (voice)

Judith Durand as (voice)

Greg Finley as (voice)

Ramón Franco as (voice)

Anneliese Goldman as (voice)

Rick Gonzales as (voice)

Tracy Metro as (voice)

Jason Pace as (voice)

Juan Pope as (voice)

Nicole Prescott as (voice)

Cheryl Tyre Smith as (voice)

John Vargas as (voice)

Tanya Vidal as (voice)

Billy 'Sly' Williams as (voice)

Ruth Zalduondo as (voice)

Ben Foster as Big Q (uncredited)

Jared Leto as Bobby (uncredited)

Mia Cottet as Lu Ann (uncredited)