Nicolas Cage as John McLoughlin

Michael Peña as Will Jimeno

Maria Bello as Donna McLoughlin

Maggie Gyllenhaal as Allison Jimeno

Danny Nucci as Officer Giraldi

Stephen Dorff as Scott Strauss

Jay Hernandez as Dominick Pezzulo

Michael Shannon as Dave Karnes

Dorothy Lyman as Allison's Mother

Peter McRobbie as Allison's Father

Wass Stevens as Pat McLoughlin

Frank Whaley as Chuck Sereika

Stoney Westmoreland as Paddy McGee

Viola Davis as Mother in Hospital with Donna

Lola Cook as Olivia Jimeno

Connor Paolo as Steven McLoughlin

Anthony Piccininni as JJ McLoughlin

Alexa Gerasimovich as Erin McLoughlin

Morgan Flynn as Caitlin McLoughlin

Armando Riesco as Antonio Rodrigues

Jon Bernthal as Christopher Amoroso

Jude Ciccolella as Inspector Fields

Julie Adams as Allison's Grandmother

Joe Starr as Subway Rider

William Jimeno as Port Authority Officer

Nick Damici as Lieutenant Kassimatis

Martin Pfefferkorn as Homeless Addict #1

Razame de la Crackers as Homeless Addict #2

Nelson Peña as Street Hood #1

Marcos Palma as Street Hood #2

Andre Ward as Port Authority Hustler

Lisa Yuen as Port Authority Tourist

Cliff Bemis as Desk Cop

Harmonica Sunbeam as 9th Avenue Hooker

Ned Eisenberg as Officer Polnicki

Nicholas Turturro as Officer Colovito

Tyree Michael Simpson as Officer Washington

Kevin Feely as Plain Clothes Officer

Mark Elliot Wilson as Street Businessman

Tawny Cypress as Bleeding Woman

Robert Blanche as WTC Desk Officer

Tom Wright as Officer Reynolds

Terry Quinn as Fire Fighter in Concourse

Ed Jewett as Wisconsin Cop

Maria Helan as Allison's Co-Worker

Brad William Henke as Allison's Brother

Patti D'Arbanville as Donna's Neighbor

Donna Murphy as Judy Jonas

Nicky Katt as Volunteer Fireman

Lucia Brawley as Will's Sister

Kimberly Scott as Sergeant King

Dara Coleman as Officer Boel

Tiffany Romano as Bianca Jimeno

Gregory Jbara as Accountant in Karnes Office

Jordan Lage as Karnes' Pastor

Tony Genaro as Will's Father

Aixa Maldonado as Will's Mother

Jay Acovone as Donna's Male Neighbor

Howard Samuelsohn as Downtown Resident

David H. Ahl as National Guard Officer at Barricade

Arthur J. Nascarella as Fire Chief at Ground Zero

Thom Prin Jr. as Fireman at Ground Zero

Steve Chappell as Figure of Jesus

William Mapother as Marine Sergeant Thomas

Thomas F. Duffy as NYC Command Centre Operator

Tommy Asher as Fireman in Hole

Charles A. Gargano as Port Authority Commander

Thomas McHale as Port Authority Sergeant

Lalanya Masters as Allison's Nurse

Greg Collins as Will's Rescue Fireman

Scott Fox as Firefighter #1 John's Rescue

Louis Raimondi as Firefighter #2 John's Rescue

Victor Spadaro as Firefighter #3 John's Rescue

John Kiernan as Firefighter #4 John's Rescue

Liz A. Randall as Will's Arrival Nurse

Roger Cross as Will's Doctor

Jossara Jinaro as Will's Operation Nurse

Joseph Esposito as Fireman Joe

Gary Stretch as John's Paramedic

Kurt Caceres as John's Rescue Fireman

John C. McGinley as Fireman