Nicolas Cage as Edward Malus

Ellen Burstyn as Sister Summersisle

Kate Beahan as Sister Willow

Frances Conroy as Dr. Moss

Molly Parker as Sister Rose / Sister Thorn

Leelee Sobieski as Sister Honey

Diane Delano as Sister Beech

Michael Wiseman as Officer Pete

Erika-Shaye Gair as Rowan Woodward

Christa Campbell as Truck Stop Waitress

Emily Holmes as Station Wagon Mom

Zemphira Gosling as Station Wagon Girl

Matthew Walker as Sea Plane Pilot

Mary Black as Sister Oak

Christine Willes as Sister Violet

Sophie Hough as Daisy

David Purvis as Ivy

Xantha Radley as Village Sister #1

Tania Saulnier as Attendant #1

Anna Van Hooft as Attendant #2

Moraea Bieber as School Girl #1

Jayda Bieber as School Girl #2

Talia Ranger as School Girl #3

Kendall Cross as Female Cop

Simon Longmore as Village Male #1

Andre Danyliu as Village Male #2

Jacqueline Robbins as Blind Twin #1

Joyce Robbins as Blind Twin #2

Aaron Eckhart as Truck Stop Patron

James Franco as Bar Guy #1

Jason Ritter as Bar Guy #2

Monique Ganderton as Rams Horn Woman (uncredited)

George A. Murphy as Villager (uncredited)

Linley Subryan as Villager (uncredited)