Sheryl Lee as Laura Palmer

Ray Wise as Leland Palmer

Mädchen Amick as Shelly Johnson

Dana Ashbrook as Bobby Briggs

Phoebe Augustine as Ronette Pulaski

David Bowie as Special Agent Phillip Jeffries

Eric DaRe as Leo Johnson

Miguel Ferrer as Albert Rosenfield

Pamela Gidley as Teresa Banks

Heather Graham as Annie Blackburn

Chris Isaak as Special Agent Chester Desmond

Moira Kelly as Donna Hayward

Peggy Lipton as Norma Jennings

David Lynch as Chief Gordon Cole

James Marshall as James Hurley

Jürgen Prochnow as Woodsman

Harry Dean Stanton as Carl Rodd

Kiefer Sutherland as Special Agent Sam Stanley

Lenny Von Dohlen as Harold Smith

Grace Zabriskie as Sarah Palmer

Kyle MacLachlan as Special Agent Dale Cooper

Frances Bay as Mrs. Tremond (Chalfont)

Catherine E. Coulson as The Log Lady

Michael J. Anderson as Man From Another Place

Frank Silva as Bob

Walter Olkewicz as Jacques Renault

Al Strobel as Philip Gerard (The One Armed Man)

Gary Hershberger as Mike Nelson

Sandra Kinder as Irene at Hap's

Chris Pedersen as Tommy

Victor Rivers as Buck

Rick Aiello as Cliff Howard

Gary Bullock as Sheriff Cable

Jon Huck as FBI Agent

Mike Malone as FBI Agent

Joe Berman as Bus Driver

Yvonne Roberts as First Prostitute

Audra L. Cooper as Second Prostitute

John Hoobler as Pilot

Kimberly Anne Cole as Lil the Dancer

Elizabeth McCarthy as Giggling Secretary

C.H. Evans as Jack at Hap's

Paige Bennett as French Girl at Hap's

G. Kenneth Davidson as Old Guy at Hap's

Ingrid Brucato as Curious Woman

Chuck McQuary as Medic

Margaret Adams as Fat Trout Neighbor

Carlton Lee Russell as Jumping Man

Calvin Lockhart as The Electrician

Jonathan J. Leppell as Mrs. Tremond's Grandson

David Brisbin as Second Woodsman

Andrea Hays as Heidi

Julee Cruise as Roadhouse Singer

Steven Hodges as Band at Roadhouse

William Ungerman as Band at Roadhouse

Joseph 'Simon' Szeibert as Band at Roadhouse

Smokey Hormel as Band at Roadhouse

Joseph L. Altruda as Band at Roadhouse

James Parks as Service Station Mechanic

Jane Jones as School Teacher

Karin Robison as Angel in Train Car

Lorna MacMillan as Angel in Red Room

Philip Anagnos as Student (uncredited)

Anne Gaybis as Dancer on Stage in 'Pink Room' (uncredited)

John Nelson as Double R Diner Customer (uncredited)

Simon Shelton as Walter Ed Pekarek (Uncredited)