Nia Vardalos as Genevieve Gernier

John Corbett as Greg Gatlin

Jason Mantzoukas as Brian Blowdell

Judah Friedlander as Dan O'Finn

Zoe Kazan as Tammy Greenwood

Stephen Guarino as Bill

Amir Arison as Bob

Gary Wilmes as Cal

Mike Starr as John

Rachel Dratch as Kathy Jeemy

Jay O. Sanders as Tim the Delivery Guy

Suzanne Shepherd as Edie

Ben Schwartz as Tammy's Date

Dan Finnerty as Grouchy Guy

Lynda Gravatt as Rose

John Tormey as Moe

Ward Horton as Mark

Isiah Whitlock Jr. as Drummer

Ian Gomez as KJ Ken

Rose Abdoo as Attractive Woman

Howard Feller as Homeless Guy

Autumn Ready Potter as Barbie

Tracy Thorpe as Giddy Woman

Kapil Bawa as Nerdy Man

Wali Collins as Desperate Customer

Miriam Tolan as Artsy Woman

Rachel Hamilton as Woman in Gallery

David Beach as Husband in Gallery

Gaetano Iacono as Big Worker

Cher Cosenza as Jill (uncredited)

Brett Berg as Punky (uncredited)

Ronnie Kroell as Tapas Server (uncredited)

Peter Conboy as Neighborhood Guy (uncredited)