Meryl Streep as Suzanne Vale

Shirley MacLaine as Doris Mann

Dennis Quaid as Jack Faulkner

Gene Hackman as Lowell Kolchek

Richard Dreyfuss as Dr. Frankenthal

Rob Reiner as Joe Pierce

Mary Wickes as Grandma

Conrad Bain as Grandpa

Annette Bening as Evelyn Ames

Simon Callow as Simon Asquith

Gary Morton as Marty Wiener

CCH Pounder as Julie Marsden

Sidney Armus as Sid Roth

Robin Bartlett as Aretha

Barbara Garrick as Carol

Anthony Heald as George Lazan

Dana Ivey as Wardrobe Mistress

Oliver Platt as Neil Bleene

Michael Ontkean as Robert Munch

Pepe Serna as Raoul

Mark Lowenthal as Bart

Michael Byers as Allen

JD Souther as Ted

George D. Wallace as Carl

Peter Onorati as Cameraman

J. Roy Helland as Make-up Man

Douglas Roberts as Soundman

Michael Haley as Assistant Director

Kathleen Gray as Cindy

Gloria Crayton as Maid at Party

Gary Matanky as Sound Editor

Marcelo Tubert as Sound Editor

John Verea as Young Intern

René Assa as Passport Official

Natalija Nogulich as Friend at Airport

Susan Forristal as Friend at Airport

Evelina Fernández as Airline Employee

Neil Machlis as Rob Sonnenfeld

Gary Jones as Fan at Party

Jane Galloway as Nurse

Steven Brill as Assistant Director

Jason Tomlins as Officer

Shelley Kirk as First Lady

Jessica Z. Diamond as Script Supervisor

Scott Frankel as Pianist at Party

Sheridan Leatherbury as Stand-In

Ken Gutstein as Director of Photography

James Deeth as Helicopter Pilot

Robert Marshall as Helicopter Pilot

Jim Cuddy as Blue Rodeo Band

Greg Keelor as Blue Rodeo Band

Bazil Donovan as Blue Rodeo Band

Mark French as Blue Rodeo Band

Bob Wiseman as Blue Rodeo Band

Jorga Caye as Western Bar Patron (uncredited)

Stanley DeSantis as Crew Member (uncredited)

Anthony DeStefanis as Savona (uncredited)

Bob Harks as Party Guest (uncredited)

Conrad Hurtt as Cowperson (uncredited)

Carrie Jachnuk as Fan at Party (uncredited)

Beau Lotterman as Soundman (uncredited)

Fred Moon as Air Plane Passenger (uncredited)

Danny Nero as Party Guest (uncredited)

Ted Raimi as Emergency Room Attendant (uncredited)

Raymond Storti as Stagehand (uncredited)