Cary Grant as Dr. Noah Praetorius

Jeanne Crain as Deborah Higgins

Finlay Currie as Shunderson

Hume Cronyn as Prof. Rodney Elwell

Walter Slezak as Prof. Barker

Sidney Blackmer as Arthur Higgins

Basil Ruysdael as Dean Lyman Brockwell

Katherine Locke as Miss James

Margaret Hamilton as Sarah Pickett (uncredited)

Jack Kelly as Student (uncredited)

Paul Lees as Student (uncredited)

Leon Tyler as Student (uncredited)

Jo Gilbert as Nurse (uncredited)

Tina Blagoi as Concertgoer (uncredited)

Helen Dickson as Concertgoer (uncredited)

Bess Flowers as Concertgoer (uncredited)

Robert Haines as Concertgoer (uncredited)

Sam Harris as Concertgoer (uncredited)

Gail Bonney as Dean's Secretary (uncredited)

William Bryant as Student Manager (uncredited)

James Carlisle as Trial Spectator (uncredited)

Julia Dean as Old Lady (uncredited)

John Davidson as Faculty Board Member (uncredited)

Wally Dean as Faculty Board Member (uncredited)

Stuart Holmes as Faculty Board Member (uncredited)

Hans Moebus as Faculty Board Member (uncredited)

Lawrence A. Williams as Faculty Board Member (uncredited)

Lawrence Dobkin as Business Manager (uncredited)

Bill Dyer as Car Attendant (uncredited)

Billy House as Coonan (uncredited)

Kay Lavelle as Bella (uncredited)

Carl M. Leviness as Concertgoer (uncredited)

Adele Longmire as Mabel (uncredited)

Joyce Mackenzie as Gussie (uncredited)

Ray Montgomery as Doctor (uncredited)

Ann Morrison as Dietician (uncredited)

Al Murphy as Photographer (uncredited)

George Offerman, Jr. as Uriah Haskins (uncredited)

Parley Baer as Toy Store Salesman (uncredited)

Loretta Russell as Concertgoer (uncredited)

Irene Seidner as Cook (uncredited)

Esther Somers as Mrs. Pegwhistle (uncredited)

Carol Varga as Cadaver (uncredited)

Maude Wallace as Night Matron (uncredited)

Will Wright as Uncle John Higgins (uncredited)

Carleton Young as Technician (uncredited)