Frank Welker as George / Duck / Cow (voice)

Amy Hill as Flower Pot Lady / Irate Woman (voice)

Ed O'Ross as Ivan the Doorman (voice)

Carlos Alazraqui as Newspaper Vendor / Conductor (voice)

Jeff Bennett as Ted (voice)

Fred Tatasciore as Mr. Bloomsberry (voice)

Nickie Bryar as Maggie / Teenage Boy (voice)

Jamie Kennedy as "Danno" Wolfe (voice)

Catherine Taber as Tina (voice)

Tim Curry as Piccadilly (voice)

Jeff McNeal as Kayla / Hog / Tonga / Layla (voice)

Cree Summer as Ms. Fisher / Cargo Pilot (voice)

Matt Lauer as Hark Hanson (voice)

Melissa Greenspan as Phone Operator (voice)

Jerry Lewis as Stationmaster (voice)

Clint Howard as Farmer Dan (voice)

Trupti Potdukhe as Anna (voice)

Phil LaMarr as Animal Park Attendant (voice)

Cam Clarke as Additional Voices (voice)

Lara Cody as Additional Voices (voice)

Greg Dawson as Additional Voices (voice)

John Kassir as Additional Voices (voice)

Cynthia Songé as Additional Voices (voice)

Steve Staley as Additional Voices (voice)