Catherine Zeta-Jones as Sandy

Justin Bartha as Aram Finklestein

Art Garfunkel as Harry Finklestein

Joanna Gleason as Roberta Finklestein

Lynn Whitfield as Laura Reilly

Andrew Cherry as Frank Jr. (Age 7)

Kate Jennings Grant as Daphne

Rob Kerkovich as Mitch

John Schneider as Trevor

Sam Robards as Frank

Alice Playten as Sensei Dana

Stephanie Szostak as Alice Marnier

Kelly Gould as Sandy young

Peter Francis James as Doctor

David Ross as Male Colleague

Marcel Simoneau as Henri

Mitch Greenberg as Rabbi

Saidah Arrika Ekulona as Lateefah

Megan Byrne as Molly Foster

Elliot Villar as Yael

Lawrence Stallings as Brent

Steve Park as John Reynolds

Dan Ziskie as Ken Gordon

Jon Norman Schneider as Runner

Thomas Middleditch as Maverick

Derek Milman as Actor #1

Richard DiBella as Actor #2

Michael Chernus as Actor #3 / Twentysomething #1

Lauren Blumenfeld as Actor #4

Carmen M. Herlihy as Actor #5 / Twentysomething #3

Kate Cullen Roberts as Twentysomething #2

Jordan Carlos as Twentysomething #4

John Ellison Conlee as Stage Manager

Skai Jackson as Museum Little Girl #1

Zoe O'Grady as Museum Little Girl #2

Fatima Ptacek as Mozambique Girl #1

Zabryna Guevara as Teacher at Museum

Lisa Paige Robinson as Susie

Marisa Redanty as Finn

Tom Riis Farrell as Terrence

Veanne Cox as Haley

Carter Roy as Waiter

Samantha Ivers as Cinnamon

Helen Coxe as Sweatsuit

Jeremy Shamos as Bill

Adam Grupper as Randy

Rachel Parker as Yoga Instructor

Hazel Anne Raymundo as Nurse

Perry Silver as Bellman

William Schloesser as Homeless Man / Flasher

Tyree Michael Simpson as Principal at Sadie's School

Heidi Blickenstaff as Morning Mom

Frank Root as Boring Interview Guy

Gabrielle Sterbenz as Kissing Girl

Marc Alan Austen as Rabbi's Cousin

William Broderick as Daphne's Husband

Saadet Işıl Aksoy as Turkish Girl in Cafe

Jonny Arriola as Waiter - Paris

James P. Anderson as Ringside Highroller (uncredited)

Steve Antonucci as Waiter (uncredited)

Pawl Bazile as Goth Hipster (uncredited)

Laura Lynn Berrios as SNN Office Worker

Robert Bizik as TV Sports Announcer (uncredited)

Danny Boushebel as VIP Boxing Fan (uncredited)

Andrew Bradley as Coffee Shop Patron (uncredited)

Daniel Burress as Coffee Shop Hipster (uncredited)

Jennifer Butler as Bowler (uncredited)

Alana Cadiz as Girl in Pop Burger (uncredited)

Kevin Cannon as Urinating Homeless Man (uncredited)

Gary Cherkassky as Club Dancer (uncredited)

Peter Conboy as Museum Worker (uncredited)

Lisamarie Costabile as Lead Yoga Student (uncredited)

Sara DeRosa as Cigarette Girl (uncredited)

Pavel Frolov as Club Dancer (uncredited)

Dennis Jay Funny as Party Guy (uncredited)

Roy William Gardner as Kissing Man (uncredited)

Adesuwa Addy Iyare as Boxing Fan (uncredited)

Edward M. Kelahan as Ringside Highroller (uncredited)

Tony Kost as Ringside Highroller (uncredited)

Joe Mancini as Highroller (uncredited)

Gregory Marcel as Trapeze Student (uncredited)

Danielle McKee as Airline Passenger (uncredited)

Chris Miskiewicz as Hipster (uncredited)

Jeffrey Mowery as Dad (uncredited)

Erik-Anders Nilsson as Teacher's Aid (uncredited)

Rich Odell as Boxing Commissioner (uncredited)

Loukas Papas as Restaurant Patron (uncredited)

Adam S. Phillips as Sportscaster (uncredited)

Joe Rusnak as Upscale Boxing Fan (uncredited)

Danny Salomon as Boxing Fan (uncredited)

Tom Stratford as Shopper (uncredited)

Isaiah Varisano as Boxing Fan (uncredited)

Jake Cherry as Frank Jr. - age 13 (uncredited)

Célia Asensio as Girlfriend - Paris