Charlotte Gainsbourg as Joe

Stellan Skarsgård as Seligman

Stacy Martin as Young Joe

Shia LaBeouf as Jerôme

Willem Dafoe as L

Udo Kier as The Waiter

Jean-Marc Barr as Debtor Gentleman

Jamie Bell as K

Mia Goth as P

Michaël Pas as Old Jerôme

Shanti Roney as Interpreter

Kate Ashfield as Therapist

Sophie Kennedy Clark as B

Lien Van De Kelder as Clerk in Horse Shop

Laura Christensen as Babysitter

Caroline Goodall as Psychologist

Christian Slater as Joe's Father

Uma Thurman as Mrs. H

Tania Carlin as Renee

Maja Arsovic as Joe - 7 Years

Ananya Berg as Joe - 10 Years

Morgan Hartley as B - 12 Years

Andrea Thomsen as Joe's Girlfriend - 12 Years

Tine Burn as Joe's Girlfriend - 12 Years

Tabea Tarbiat as Valeria Messalina

Janine Romanowski as The Whore of Babylon

Lawrence Sheldon as Man 1 in Car

Ivan Pecnik as Man 2 in Car

Jonathan Sawdon as Man 3 in Car

Christopher Craig as Man 4 in Car

Jacob Levin-Christensen as Marcel - 3 Years

Kookie Ryan as N - Black Man

Papou as Black Man 2

Nicole Sandweg as Madame

Sarah Soetaert as Boss

Sami Loris as Doctor 2

Christine Urspruch as Litte My

Daniela Lebang as Brunhelda

Omar Shargawi as Thug 1

Marcus Jakovljevic as Thug 2

Conny Dachs as Debtor Gets Whipped

Severin von Hoensbroech as Debtor in Greenhouse