Billy Crudup as FH

Samantha Morton as Michelle

Jack Black as Georgie

Denis Leary as Wayne

Dennis Hopper as Bill

Holly Hunter as Mira

Michael Shannon as Dundun

John Ventimiglia as McInnes

Will Patton as John Smith

Miranda July as Black-Eyed Nurse

Mark Webber as Jack Hotel

Scott Oster as Stan

Ben Shenkman as Tom

Steve Buck as Richard

Rebecca Kimball as Mennonite wife

David Urrutia as Mennonite husband

Denis Johnson as Terrence Weber

Yvette Mercedes as E.R. Nurse

Omar Koury as E.R. Doctor