Al Pacino as Danny Collins

Annette Bening as Mary Sinclair

Christopher Plummer as Frank Grubman

Jennifer Garner as Samantha Leigh Donnelly

Bobby Cannavale as Tom Donnelly

Nick Offerman as Guy DeLoach

Josh Peck as Nicky Ernst

Katarina Čas as Sophie

Giselle Eisenberg as Hope Donnelly

Melissa Benoist as Jamie

Scott Lawrence as Dr. Ryan Kurtz

Brian Thomas Smith as Judd

Michael Patrick McGill as Neighbor Steve

Kiff VandenHeuvel as Marty

Eric Michael Roy as Young Danny Collins

Davide Donatiello as Young Danny Collins

Eric Lange as Dr. Silverman

Aarti Mann as Nurse Nikita

Joshua Sternlicht as Josh the Bartender

Travis Johns as Roadie

Tim Jo as Tim

Hiroshi Moroto as Autograph Seeker

Margy Moore as Hotel Bar Patron

Eric Newnham as Hotel Bar Patron

Francine Levinson as Night Club Fan

Hal Alpert as Night Club Fan

Henri C. Wittelsohn as Night Club Fan

Patrick Kudej as Chime In Magazine Intern

Carmel Echols as Danny's Background Singer

Judith Hill as Danny's Background Singer

Kari Kimmel as Danny's Background Singer

Don Was as Danny's Band

CJ Vanston as Danny's Band

Kenny Aronoff as Danny's Band

Tim Pierce as Danny's Band

Mindi Abair as Danny's Band

Bill Cantos as Danny's Band

George Doering as Danny's Band

Darrell Leonard as Danny's Band

Kristin Brock as Kissing Couple (uncredited)

Elsi Eng as Eye Candy (uncredited)

Chachi Hildén as Ballerina (uncredited)

Laura Krystine as Ballerina (uncredited)

Anne McDaniels as Danny's Doll (uncredited)

Roz McHenry as Red Vine Lady #1 (uncredited)

Elaine Partnow as Red Vine Lady #2 (uncredited)

Jane Shayne as Red Vine Lady #3 (uncredited)

Cassandra Starr as Groupie (uncredited)

Linda Wang as Asian Fan #2 (uncredited)

Richard Allan Jones as Party Guest (uncredited)

Arthur Bedran as Boy Band Member