John Candy as Buck Russell

Jean Louisa Kelly as Tia Russell

Gaby Hoffmann as Maizy Russell

Macaulay Culkin as Miles Russell

Amy Madigan as Chanice Kobolowski

Elaine Bromka as Cindy Russell

Garrett M. Brown as Bob Russell

Laurie Metcalf as Marcie Dahlgren-Frost

Jay Underwood as Bug

Brian Tarantina as E. Roger Coswell

Mike Starr as Pooter-the-Clown

Suzanne Shepherd as Mrs. Hogarth

William Windom as Mr. Hatfield (voice)

Dennis Cockrum as Pal

Joel Robinson as Miles' Friend #1

Colin Baumgartner as Miles' Friend #2

Erik Whipple as Miles' Friend #3

Mark Rosenthal as Party Boy #1

Doug von Nessen as Party Boy #2

Wayne Kneeland as Party Boy #3

Gigi Casler as Party Girl in Bedroom

LaVerne Anderson as Party Girl #1

Gina Doctor as Party Girl #2

Rachel Thompson Perrine as Party Girl #3

Ron Payne as Maizy's Teacher

Jane Vickerilla as Teacher

Kyle Lewis Eastman as School Child

Dana Taylor as School Child

Jennifer Kane as School Child

Christen Loftis as School Child

Genae Affrunti as School Child

Anna Chlumsky as School Child

Patricia Arquette as Additional Voices (voice)

Jack Blessing as Additional Voices (voice)

Devon Odessa as Additional Voices (voice)

Ryan Goldstein as School Child (uncredited)

Arnold F. Turner as Additional Voices (voice)