Robert De Niro as Rupert Pupkin

Jerry Lewis as Jerry Langford

Diahnne Abbott as Rita

Sandra Bernhard as Masha

Shelley Hack as Cathy Long

Frederick de Cordova as Bert Thomas

Ed Herlihy as Ed Herlihy

Lou Brown as Band Leader

Loretta Tupper as Stage Door Fan

Peter Potulski as Stage Door Fan

Vinnie Gonzales as Stage Door Fan

Whitey Ryan as Stage Door Guard

Doc Lawless as Chauffeur

Marta Heflin as Young Girl

Katherine Wallach as Autograph Seeker

Charles Kaleina as Autograph Seeker

Richard Baratz as Caricaturist

Catherine Scorsese as Rupert's Mom (voice)

Cathy Scorsese as Dolores

Chuck Low as Man in Chinese Restaurant

Liza Minnelli as Liza Minnelli

Leslie Levinson as Roberta Posner

Alan Potashnick as Man at Telephone

Michael Kolba as Man at Telephone

Robert Colston as Man at Telephone

Ramon Rodriguez as Man at Telephone

Chuck Coop as Man at Telephone

Sel Vitella as Man at Telephone

Margo Winkler as Receptionist

Tony Boschetti as Mr. Gangemi

Mick Jones as Street Scum

Joe Strummer as Street Scum

Paul Simonon as Street Scum

Kosmo Vinyl as Street Scum

Ellen Foley as Street Scum

Pearl Harbour as Street Scum

Gaby Salter as Street Scum

Jerry Baxter-Worman as Street Scum

Don Letts as Street Scum

Matt Russo as Cabbie

Thelma Lee as Woman in Telephone Booth

Joyce Brothers as Dr. Joyce Brothers

George Kapp as Mystery Guest

Victor Borge as Victor Borge

Ralph Monaco as Raymond Wirtz

Rob-Jamere Wess as Security Guard

Kim Chan as Jonno

Audrey Dummett as Cook

June Prud'Homme as Audrey

Edgar J. Scherick as Wilson Crockett

Thomas M. Tolan as Gerrity

Ray Dittrich as Giardello

Richard Dioguardi as Captain Burke

Jay Julien as Langford's Lawyer

Harry J. Ufland as Langford's Agent

Scotty Bloch as Crockett's Secretary

Jim Lyness as Ticket Taker

Bill Minkin as McCabe

Diane Rachell as McCabe's Wife

Dennis Mulligan as Plainclothesman

Tony Devon as Plainclothesman

Peter Fain as Plainclothesman

Michael F. Stodden as Plainclothesman

Gerard Murphy as Plainclothesman

Jimmy Raitt as Stage Manager

Martin Scorsese as TV Director

Tony Randall as Tony Randall

Charles Scorsese as First Man at Bar

Mardik Martin as Second Man at Bar

William Jorgensen as Newsman (voice)

Marvin Scott as Newsman (voice)

Chuck Stevens as Newsman (voice)

William Littauer as Newsman (voice)

Jeff David as Announcer (voice)