Lionel Barrymore as Dr. Josiah Glass

Jean Arthur as Maria Theresa 'Terry' O'Reilly

Chester Morris as Jeff Crane

Joseph Calleia as Sonny 'Dinkie' Black

Paul Kelly as Special Agent James Duff

Lewis Stone as Prison Warden

Paul Hurst as Rufe Parker

George E. Stone as Butch

Sam Baker as Mose Jones

William Bailey as Federal Agent (uncredited)

Brooks Benedict as Bar Patron (uncredited)

Ed Brady as Convict in Prison (uncredited)

Lane Chandler as Train Conductor (uncredited)

Cora Sue Collins as Little Girl (uncredited)

Helene Costello as Convict Wife (uncredited)

Nell Craig as Duff's Secretary with Telegram (uncredited)

Frank Darien as Dr. Hale - Plastic Surgeon (uncredited)

James Flavin as Flavin - Federal Agent (uncredited)

Harry Geise as Convict (uncredited)

John George as Convict (uncredited)

Jonathan Hale as Prison Board Member (uncredited)

Henry Hall as Restaurant Patron (uncredited)

Lillian Harmer as Mrs. Higgins (uncredited)

Eddie Hart as Eddie - Sonny's Henchman (uncredited)

Edward Hearn as Policeman in Pursuing Car (uncredited)

Al Hill as Al - Sonny's Henchman (uncredited)

Arthur Housman as Scottsdale Bar Drunk (uncredited)

William Irving as Federal Agent (uncredited)

Selmer Jackson as Simpson - Prison Board Member (uncredited)

Gladden James as Federal Agent (uncredited)

John Kelly as Federal Agent / Truck Driver Smuggling Gun (uncredited)

Anderson Lawler as Higgins - Federal Agent (uncredited)

Frank McGlynn Jr. as Federal Agent (uncredited)

Larry McGrath as

Greta Meyer as Glass' Housekeeper (uncredited)

Bob Montgomery as Brian - Sonny's Henchman (uncredited)

Bert Moorhouse as Federal Agent (uncredited)

Frank Moran as Moran - Prison Guard (uncredited)

Philip Morris as Government Agent (uncredited)

James C. Morton as Road House Patron (uncredited)

Pat O'Malley as Federal Agent (uncredited)

Jack Pennick as Bus Driver (uncredited)

Lee Phelps as Tower Guard with Machine Gun (uncredited)

Russ Powell as McGinnis - Hotel Bartender (uncredited)

Stanley Price as Sonny's Henchman (uncredited)

Frank Rice as Cab Driver (uncredited)

Bert Roach as Salesman on Bus Annoying Terry (uncredited)

Teru Shimada as Sam - Sonny's Japanese Houseboy (uncredited)

Landers Stevens as Federal Man (uncredited)

Carl Stockdale as Train Conductor (uncredited)

Billy Sullivan as Undetermined Role (uncredited)

Zeffie Tilbury as Deaf Woman in Scottsdale Bar (uncredited)

Dorothy Vernon as Restaurant Patron (uncredited)

Larry Wheat as Andrews - Prison Board Member (uncredited)

Bill Wolfe as Man on Dance Floor (uncredited)

William Worthington as Prison Board Member (uncredited)

Tammany Young as Bartender (uncredited)

Frank Bruno as Extra Leaving Theater (uncredited)