Jane Krakowski as Claire's Mom

Richard Griffiths as Santa Claus

Steve Whitmire as Kermit the Frog / Rizzo the Rat / Statler / Beaker (voice)

Madison Pettis as Claire

Whoopi Goldberg as Taxi Driver

Dave Goelz as The Great Gonzo / Waldorf / Dr. Bunsen Honeydew / Zoot (voice)

Bill Barretta as Pepe the Prawn / Swedish Chef / Rowlf / Dr. Teeth / Bobo the Bear / Husband Pigeon (voice)

Michael Bloomberg as Himself (as Mayor Michael Bloomberg)

Eric Jacobson as Fozzie Bear / Miss Piggy / Animal / Sam the Eagle (voice)

Matt Vogel as Floyd Pepper / Lew Zealand / Crazy Harry / Robin the Frog / Son Pigeon / Additional Muppets (voice)

David Rudman as Scooter / Janice / Additional Muppets (voice)

Nathan Lane as Officer Meany

Jesse L. Martin as Postal Worker

Petra Němcová as Beaker's Girlfriend

Steve Schirripa as Mobster

Tony Sirico as Mobster

Uma Thurman as Joy

Paul Williams as Elf

Pam Arciero as Additional Muppets (voice)

Heather Asch as Additional Muppets (voice)

Tyler Bunch as Wife Pigeon / Additional Muppets (voice)

Leslie Carrara-Rudolph as Additional Muppets (voice)

Stephanie D'Abruzzo as Additional Muppets (voice)

James Godwin as Additional Muppets (voice)

James J. Kroupa as Additional Muppets (voice)

Tim Lagasse as Additional Muppets (voice)

Peter Linz as Additional Muppets (voice)

Noel MacNeal as Sweetums / Additional Muppets (voice)

Jim Martin as Additional Muppets (voice)

Paul McGinnis as Additional Muppets (voice)

Martin P. Robinson as Sweetums / Additional Muppets (voice)

Nadine Ellis as Dancer

Kevin Sateri as Dancer

Douglas Caldwell as Dancer

Mary Ann Lamb as Dancer

Terrance Reddick as Dancer

Warren Adams as Dancer

Paul Becker as Postal Dancer

Peter Conboy as Holiday Commuter

Paul T. Gosselin as Postal Customer

Bill Timoney as Additional Voices

Guy Veryzer as Mailman