Edward G. Robinson as Caesar Enrico 'Rico' Bandello aka 'Little Caesar'

Douglas Fairbanks Jr. as Joe Massara

Glenda Farrell as Olga Stassoff

William Collier Jr. as Tony Passa

Sidney Blackmer as Big Boy

Ralph Ince as Pete Montana

Thomas E. Jackson as Sergeant Flaherty

Stanley Fields as Sam Vettori

Maurice Black as Little Arnie Lorch

George E. Stone as Otero

Armand Kaliz as De Voss

Nicholas Bela as Ritz Colonna

Ernie Adams as Cashier (uncredited)

Elmer Ballard as Undetermined Role (uncredited)

Ferike Boros as Mrs. Passa (uncredited)

Kernan Cripps as Detective (uncredited)

George Daly as Machine-Gunner (uncredited)

Adolph Faylauer as New Year's Celebrant (uncredited)

Ben Hendricks Jr. as Kid Bean (uncredited)

Al Hill as Rico's 'Butler' (uncredited)

Lucille La Verne as Ma Magdalena (uncredited)

Gladys Lloyd as McClure Guest (uncredited)

Noel Madison as Killer Peppi (uncredited)

Tom McGuire as Detective on Phone (uncredited)

Louis Natheaux as Hood (uncredited)

Henry Sedley as Scabby (uncredited)

Gay Sheridan as Nightclub Patron (uncredited)

Larry Steers as McClure Guest (uncredited)

Landers Stevens as Alvin McClure - Crime Commissioner (uncredited)

Mike Tellegen as Bodyguard (uncredited)

Bob Walker as Lorch Henchman (uncredited)