The Big Empty is a 2005 short film starring Selma Blair about a woman with an unusual condition that baffles scientists and laymen alike. It was written, directed and produced by Lisa Chang and Newton Thomas Sigel. It is based on the short story The Specialist, by Alison Smith. It was executive produced by George Clooney and Steven Soderbergh.
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Selma Blair as Alice

Elias Koteas as The Specialist

Richard Kind as Talk Show Host

Gabriel Mann as The Thoughtful Man

Richmond Arquette as Gynecologist

Hugh Laurie as Doctor

Grant Heslov as Doctor

Ezra Buzzington as Cartographer

Haskell Wexler as Bookstore Customer

Simon Cole as Arctic Explorer

Linda Bisesti as Nurse

David Doumeng as Anchor

Rita Taggart as Bookstore Co-Worker

Parvesh Cheena as Sports Fan

Candy Clark as Mother
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