Tom Cruise as Nick Morton

Annabelle Wallis as Jennifer Halsey

Sofia Boutella as Ahmanet

Jake Johnson as Chris Vail

Courtney B. Vance as Colonel Greenway

Russell Crowe as Henry Jekyll / Edward Hyde

Marwan Kenzari as Malik

Neil Maskell as Dr. Whemple

Javier Botet as Set

Andrew Brooke as Mr. Brooke

Selva Rasalingam as King Menehptre

Shanina Shaik as Arabian Princess

Dylan Smith as Pilot

Hadrian Howard as MP

Rez Kempton as Construction Manager

Bella Ava Georgiou as Fourth Technician

David Burnett as Tunnel Agent

Stephen Thompson as First Man

James Arama as Second Man

Vera Chok as Prodigium Tech

Sean Cameron Michael as Archaeologist

Martin Bishop as Senior Technician

Simon Atherton as Crusader

Matthew Wilkas as Reporter

Sohm Kapila as Reporter

Erol Ismail as Ahmanet's Warrior

Parker Sawyers as Co-Pilot

Rhona Croker as Helen

Timothy Allsop as Worker

Grace Chilton as Woman in Toilet

Hannah Ankrah as Woman in Toilet

Dylan Kussman as Writer Tech

Peter Lofsgard as Spider Technician

Shane Zaza as Technician

Alice Hewkin as Technician

Daniel Tuite as Prodigium Technician

Noof Ousellam as Technician in Chamber

Maryam Grace as Female Tech

Sonya Cullingford as Undead

Fionn Cox-Davies as Undead

Neus Gil Cortes as Undead

Emily Thompson-Smith as Undead

Stéphane Deheselle as Undead

Madeleine Fairminer as Undead

Michèle Paleta Rhyner as Undead

Michael Haydon as Tourist (uncredited)

Jason Matthewson as Museum Guy (uncredited)

Kelly Burke as Museum Visitor (uncredited)

Chasty Ballesteros as Kira Lee (uncredited)

Emma Louise Saunders as Museum Visitor (uncredited)

Alaa Safi as Sickle Slave