Wallace Beery as Louis 'Slaughterhouse' Scorpio

Lewis Stone as Richard 'Newt' Newton - Attorney at Law

Johnny Mack Brown as Hank Rogers

Jean Harlow as Anne Courtland

Marjorie Rambeau as Peaches

Paul Hurst as Nick Mizoski - the Gouger

Clark Gable as Carl Luckner

Ralph Bellamy as Johnny Franks

John Miljan as Joe Colimo

DeWitt Jennings as Chief of Police Donlin

Murray Kinnell as Metz - the Dummy

Fletcher Norton as Jimmy Delano

Louis Natheaux as Eddie

Frank McGlynn Sr. as Judge

Theodore von Eltz as District Attorney Keeler

Lynton Brent as Reporter (uncredited)

Charles Giblyn as Mr. Simms - Ballistics Expert (uncredited)

Joseph W. Girard as Official (uncredited)

Betty Lawson as Undertermined Secondary Role (uncredited)

Tom London as Blackjacking Gangster (uncredited)

George Magrill as Police Guard at Jailhouse (uncredited)

Lee Phelps as Smelts - Waiter (uncredited)

Oscar Rudolph as Ivan Colimo (uncredited)

Hector Sarno as Finko (uncredited)

Carol Tevis as Manicurist (uncredited)

Walter Walker as Onlooker in Courtroom (uncredited)

S.D. Wilcox as Protesting Man in Courtroom (uncredited)