Jennifer Aniston as Claire Bennett

Adriana Barraza as Silvana

Anna Kendrick as Nina Collins

Sam Worthington as Roy Collins

Mamie Gummer as Bonnie

Felicity Huffman as Annette

William H. Macy as Leonard

Chris Messina as Jason Bennett

Lucy Punch as Nurse Gayle

Britt Robertson as Becky

Paula Cale as Carol

Ashley Crow as Stephanie

Manuel Garcia-Rulfo as Arturo

Camille Guaty as Tina

Allen Maldonado as Buddy

Camille Mana as Nurse Salazar

Julio Oscar Mechoso as Pharmacist

Evan O'Toole as Casey Collins

Lizzie Peet as Gail

Pepe Serna as Nuncio

Misty Upham as Liz

Rose Abdoo as Innocencia

Alma Martinez as Irma

Andrew Elvis Miller as Border Patrol Officer

Louie Novoa as Waiter

Laura Putney as Clinic Worker

Robert Zimiga as Border Patrol Officer #2