Charlize Theron as Dr. Wren Petersen

Javier Bardem as Dr. Miguel Leon

Jean Reno as Dr. Mehmet Love

Adèle Exarchopoulos as Ellen

Jared Harris as Dr. Farber

Hopper Penn as Billy Boggs

Denise Newman as Sarie

Mark De Villiers as Wren's Father

Amy Harries-Jones as Young Wren

Obed Baloyi as Atef

Merritt Wever as Marlee

Vaneshran Arumugam as East Indian UN Staffer

Tinarie Van Wyk-Loots as UN Staffer

Sebelethu Bonkolo as Sam

Sibongile Mlambo as Assatu

Bill Gerber as UN Representative

Bronwyn Reed as Catholic School Girl

Chris Gxalaba as Oom Pieter

Fiona Ramsay as Beatrice

Sarah Muhoho as Sierra Leone Villager

Linda Sokhulu as Triage Nurse

Ebby Weyime as Nurse

Andile Vuyolwethu Pakade as Youth Soldier

Elodie Venece as Priya

Oscar Best as Dr. Brown

Asante Mabuza as Mena