Jessica Chastain as Antonina Żabińska

Daniel Brühl as Lutz Heck

Johan Heldenbergh as Jan Żabiński

Michael McElhatton as Jerzyk

Timothy Radford as Ryszard Żabiński (Younger)

Efrat Dor as Magda Gross

Iddo Goldberg as Maurycy Fraenkel

Shira Haas as Urszula

Val Maloku as Ryszard Zabinski

Martha Issová as Regina Kenigswein

Frederick Preston as Miecio Kenigswein

Goran Kostić as Mr. Kinszerbaum

Anna Rust as The Zebra Woman

Daniel Ratimorský as Samuel Kenigswein

Theo Preston as Stefcio Kenigswein

Viktoria Zakharyanova as Stefania Keningswein

Arnošt Goldflam as Dr. Janusz Korczak

Marián Mitaš as Stefan

Martin Hofmann as Szymon Tenenbaum

Jitka Smutná as Pietrasia

Waldemar Kobus as Dr. Ziegler

Viktorie Jenicková as Teresa Zabinska (2 years old)

Adira B. Cole Abbett as Teresa Zabinska (9 months old)

Hana Pindurová as Teresa Zabinska (Baby)

Slavko Sobin as Mr. Keller

Alena Mihulová as Marysia Aszer

Nataša Burger as Roza Anzelowna

Hana Frejková as Roza's Mother

Magdalena Lamparska as Wanda Englert

Vilma Frantová as Zofia Kossak

Magdaléna Sidonová as Janina Rabbe

Petra Bučková as Wanda Filipowicz

Roman Vejdovec as Senior German Officer

Ladislav Hampl as Ghetto Gate #1 Guard

Václav Neužil as Ghetto Gate #2 Guard

Brian Caspe as Ghetto Soldier #1

Ester Kočičková as Eugenia Wasowska

Roman Horák as German Soldier #1

Jakub Šmíd as Ghetto Soldier #2

Gabriel Cohen as Smoking German Soldier #1

Josef Guruncz as Smoking German Soldier #2

Patricia Kalis as Polish woman

Diego Delpiano as Young Rys Zabinski (uncredited)