Judy Greer as Shannon

Natasha Lyonne as Martha

Aubrey Plaza as Kelly

Clea DuVall as Regina

Ron Livingston as Edwin

Allison Tolman as Ruby

Molly Shannon as Margaret Lipka

Fred Armisen as Gerald

Jessica St. Clair as Kristen

Malcolm Barrett as Eric

Edward Barbanell as Jerry

John Roohinian as Noah

Davenia McFadden as Denise

Jon Daly as Boris Lipka

Paul Bates as Henry

Barbara Drotow as Kasia Lipka

Michael Hitchcock as David

Beth Grant as Tilda

Dave Silva as Motel Clerk

Kumail Nanjiani as Damon

Maria Olsen as Softball Player (uncredited)

Henry Miller Hansen as Krav Maga Student (uncredited)

Teresa R. Parker as Bartender (uncredited)

William R Phillips as Scott (uncredited)