Charles Laughton as Dr. Moreau

Richard Arlen as Edward Parker

Leila Hyams as Ruth Thomas

Bela Lugosi as The Sayer of the Law

Kathleen Burke as Lota the Panther Woman

Arthur Hohl as Montgomery

Stanley Fields as Capt. Davies

Paul Hurst as Capt. Donahue

Hans Steinke as Ouran

Tetsu Komai as M`ling

George Irving as Consul

Jack Bardette as Undetermined Role (uncredited)

Evangelus Berbas as Undetermined Role (uncredited)

Joe Bonomo as Beast (uncredited)

Buster Brodie as Pig Man - a Little Beast (uncredited)

Jacob Dance as Beast (uncredited)

James Dime as Seaman (uncredited)

Harry Ekezian as Gola (uncredited)

Charles Gemora as Gorilla on Pier (uncredited)

John George as Beast (uncredited)

Rosemary Grimes as Samoan Girl (uncredited)

Robert P. Kerr as Undetermined Role (uncredited)

Bob Kortman as Mr. Hogan (uncredited)

Robert Milasch as Beast (uncredited)

Constantine Romanoff as Beast (uncredited)

Schlitzie as Furry Manimal (uncredited)

Jack Walters as Undetermined Role (uncredited)

Duke York as Beast (uncredited)