Lionel Atwill as Dr. Jerry Xavier

Fay Wray as Joanne Xavier

Lee Tracy as Lee Taylor

Preston Foster as Dr. Wells

John Wray as Dr. Haines

Harry Beresford as Dr. Duke

Arthur Edmund Carewe as Dr. Rowitz

Leila Bennett as Mamie

Robert Warwick as Commissioner Stevens

George Rosener as Otto, Dr. Xavier's Butler

Willard Robertson as Detective O'Halloran

Thomas E. Jackson as Daily World Editor

Harry Holman as Mike, Waterfront Policeman

Mae Busch as Cathouse Madame

Tom Dugan as Sheriff

Raoul Freeman as Morgue Detective (Uncredited)

Selmer Jackson as Willard Keefe, Daily World Night Editor (Uncredited)

Charles McMurphy as Detective at Headquarters (Uncredited)

Ky Robinson as Morgue Detective (Uncredited)

Louise Beavers as Louise (Uncredited)