Damon Gameau as Himself

Stephen Fry as The Sugar Family Sketch

Brenton Thwaites as The Liver Sketch

Isabel Lucas as Sugary Words

Jessica Marais as Sugar Emotion Sketch

John Leary as Ballet Business Man

Nick Batzias as Father

Katie Batzias as Mother

Annalise Braakensiek as Bikini girl on beach

Kieron Rooney as Scientist in Lab

Gary Taubes as Self / Investigative Science Journalist / Author, Why We Get Fat

David Wolfe as Self

Kathleen DesMaisons, Ph.D. as Self / President, Radiant Recovery

Thomas W. Campbell as Self / Author, "My Big TOE" / Retired NASA Physicist

Professor Nick Allen as Self / Psychological Science, U. Melbourne

Kelly Brownell as Self / Dean, Sanford School of Public Policy, Duke U.

Nyurpaya Kaika Burton as Self

Angela Hammons as Self

Larry Hammons as Self

Aaron Matheson as Self / Wellness Leader

Howard Moskowitz as Self / Chairman, iNovum LLC

Michael Moss as Self / Author "Salt Sugar Fat"

Barry Popkin as Self / Professor of Nutrition, UNC

Danielle R. Reed as Self / Member of Monell Chemical Senses Center

Jean-Marc Schwartz as Self / Professor, Touro University, CA

Dr. John L. Sievenpiper as Self / Physician Scientist, Li Ka Shing Knowledge Institute

Dr. Edwin Smith as Self / Dentist, Kentucky

Kimber Stanhope as Self / Research Scientist / PhD. Nutritional Biology

Eric Stice as Senior Research Scientist

Maurice Thompson as Self / Amata Store Manager

John Tungku Tregenza as Self / Aboriginal Community Development Worker

Inawinytji Williamson as Self / OAM

Hugh Jackman as Self