Morgan Spurlock as Self

Daryl Isaacs as Self - Internal Medicine

Lisa Ganjhu as Self - Gastroenterologist & Hepatologist

Stephen Siegel as Self - Cardiologist

Bridget Bennett as Self - Nutritionist & Dietician

Eric Rowley as Self - Exercise Physiologist

Mark Fenton as Self - Former Editor: Walking Magazine

Alexandra Jamieson as Self - Morgan's girlfriend & Vegan Chef

John Banzhaf as Self - Law Professor, George Washington University

David Satcher as Self - Former U.S. Surgeon General

Lisa Young as Self - Professor of Nutrition, New York University

Kelly Brownell as Self - Professor, Yale Center for Eating and Weight Disorders

Jacob Sullum as Self - Senior Editor, Reason Magazine

Tommy Thompson as Self - Secretary of Health and Human Services

William J. Klish as Self - Head of Dept. of Medicine, Texas Children's Hospital

Ron English as Self - Artistic Genius