Robert De Niro as Father Des Spellacy

Robert Duvall as Det. Tom Spellacy

Charles Durning as Jack Amsterdam

Kenneth McMillan as Frank Crotty

Ed Flanders as Dan T. Campion

Cyril Cusack as Cardinal Danaher

Burgess Meredith as Msgr. Seamus Fargo

Rose Gregorio as Brenda Samuels

Dan Hedaya as Howard Terkel

Gwen Van Dam as Mrs. Fazenda

Thomas Hill as Mr. Fazenda

Jeanette Nolan as Mrs. Spellacy

Jorge Cervera Jr. as Eduardo Duarte

Susan Myers as Bride

Louisa Moritz as Whore

Darwyn Carson as Loran Keane

James Hong as Coroner Wong

Pat Corley as Sonny McDonough

Missy Cleveland as Lois Fazenda - Murder Victim

Jeff Howard as Priest #2