Ellen Burstyn as Nana

Kieran Culkin as Brandon McCarthy

Julie Delpy as Dina

Danny DeVito as Dave Schmerz

Greta Gerwig as Dawn Wiener

Tracy Letts as Danny

Zosia Mamet as Zoe

Keaton Nigel Cooke as Remi

Haraldo Alvarez as Luis

Rigoberto Garcia as Jose

Dain Victorianio as Jose Luis

Connor Long as Tommy

Bridget Brown as April

Sharon Washington as Phillips

Devin Druid as Dwight

Trey Silver as Peter Jacobson

Ari Graynor as Carol Steinhart

Birkett Turton as Director

Samrat Chakrabarti as Dr. Farhard Rahman

Trey Gerrald as Zeno

Clara Mamet as Lina

Katherine Reis as Rafa

Charlie Tahan as Warren

Melo Ludwig as Young Nana

Michael James Shaw as Fantasy

Marcella Lowery as Yvette

Jen Ponton as Kristy

Alexis Suarez as Police Officer

Andrew Pang as Wong

Scott Martin as Street Vendor

Steven Ted Beckler as FBI Agent

Bridget M. Brown as April

Anna Baryshnikov as Tara