Dudley Moore as Harvey Orchid / Herschel

Laraine Newman as Zoey / Zerelda

James Coco as Hyssop

Paul Sand as God's Angel

Jack Gilford as Tailor

Dom DeLuise as Shadrach

John Houseman as The Archangel

Madeline Kahn as The Witch

David L. Lander as The Beggar

Richard Pryor as Pharaoh

John Ritter as Satan (The Devil)

Richard B. Shull as Jethro

William Watson as Bandit

Tanya Boyd as Princess

Sam Weisman as Talent Coordinator

Jeffrey Jacquet as Young Pharaoh

Howard Mann as High Priest

Charles Thomas Murphy as Tour Guide

Hap Lawrence as Blind Man

David Murphy as Teenager

Tom Baker as Egyptian Captain

Andrea Martin as Zipporah

Stan Ross as Mohammed

Sandy Ward as Taskmaster

Lee Wilkof as Townsperson

Maryedith Burrell as Villager

Ruth Manning as Landlady

Rod McCary as Hittite Emissary

Brion James as Guard at Banquet

Lois Robbins as 1st Maiden

Shelley Johnson as 2nd Maiden

Michael Champion as Sodom Sentry

Lauren Friedman as Moses' Mother

Ion Teodorescu as Court Magician

Nicholas Mele as Israeli Photographer

Danny Goldman as Scribe

Larry Gelman as Shepherd

Alexander Lockwood as Elderly Man

Walker Edmiston as God (voice)