Jon Hamm as Tim Jones

Isla Fisher as Karen Gaffney

Zach Galifianakis as Jeff Gaffney

Gal Gadot as Natalie Jones

Patton Oswalt as Bruce Springstein / Scorpion

Matt Walsh as Dan Craverston

Maribeth Monroe as Meg Craverston

Kevin Dunn as Carl Pronger

Jona Xiao as Stacey Chung

Ming Zhao as Scorpion's Girlfriend

Richard Regan Paul as Sanjay

Henry Boston as Patrick Gaffney

Jack McQuaid as Mikey Gaffney

Ari Shaffir as Oren

Marc Grapey as Bernie

Ying He as Mrs. Lu

Yi Dong Hian as Mr. Lu

Lauren Revard as Margaret

Rishik Patel as Dhameer

Dayo Abanikanda as Cool Man

Bobby Lee as Ricky Lu

Karina Bonnefil as Waitress

Darin Cooper as Detective

Angela Ray as Police Officer

Amy Block as Neighborhood Mom

Cullen Moss as Guard #1

Matt McHugh as Guard #2

Sharon Gee as Stacey's Mom

Scott Allen Perry as Henchman

Massi Furlan as Henchman

Andre Pushkin as Henchman

Andrew Farmer as HR Staffer #1

Pamela Conover as HR Staffer #2

Kristina Case as Wife

Adrienne Ballenger as Hostess

Harry Galifianakis as Diner Customer

Jordan Eli Arellano as Morroccan Citizen (uncredited)

Derek Carver as Bartender (uncredited)

Jeff Chase as Misha (uncredited)

William Curtis Coppersmith as Henchman (uncredited)

Jeremy Degree as Security Officer (uncredited)

Gregory Fears as Security Guard (uncredited)

Fred Galle as Jack (uncredited)

Inder Kumar as Coffee Patron (uncredited)

BreeAnna Marie as Pool Reveler / Party Goer (uncredited)

Amy Parrish as Jill (uncredited)

Glenn Walkup as Henchman (uncredited)

Carrie Walrond Hood as Bridgett O'Keefe (uncredited)

Michael Liu as Yang

Sharon Jones as Performer "I'll Be Around"