Xavier Samuel as Adam "The Monster"

Carrie-Anne Moss as Elizabeth Frankenstein

Danny Huston as Victor Frankenstein

Tony Todd as Eddie

Mckenna Grace as Molly

Maya Erskine as Wanda

Matthew Jacobs as Dr. Marcus

David Pressler as Dr. Pretorius

Peter Sudarso as Guard 1

Steve Hart as Guard 2

Jeordie White as Skid Row Man

James Lew as Hotel Manager

Mary Gallagher as Amy Johnson

Rob Mars as Officer Crawford

Ron Roggé as Officer Woodcock

Myke Michaels as Vigilante Mob 1

John Lacy as Mark Rubin

Jeff Hilliard as Officer Banks

Jorge-Luis Pallo as Officer Lincoln

Ladell Preston as Gangbanger 1

Jay Hawkins as Gangbanger 2

Jerry Ying as Paramedic

Nils Allen Stewart as Construction Worker