Spencer Tracy as Grant Matthews

Katharine Hepburn as Mary Matthews

Van Johnson as Spike McManus

Angela Lansbury as Kay Thorndyke

Adolphe Menjou as Jim Conover

Lewis Stone as Sam Thorndyke

Margaret Hamilton as Norah

Charles Dingle as Bill Nolard Hardy

Charles Lane as Blink Moran

Howard Smith as Sam I. Parrish

Irving Bacon as Buck Swenson

Maidel Turner as Lulubelle Alexander

Raymond Walburn as Judge Alexander

Ellen Ross as Secretary

Eve Whitney as Secretary

Arthur O'Connell as First Reporter

Frank Mayo as City Official

Tor Johnson as Wrestler

Patti Brady as Joyce Matthews

Georgie Nokes as Grant Matthews Jr.

Carl Switzer as Bellboy

Tom Fadden as Waiter

Tom Pedi as Barber

Jerry Schumacher as Newsreel Cameraman

Harry Anderson as Photographer (uncredited)

Stanley Andrews as Senator (uncredited)

Herschel Graham as Assistant Cameraman (uncredited)

Eddie Kane as Television Prompter (uncredited)

Roger Moore as Photographer (uncredited)

Charles Sherlock as Photographer (uncredited)

Dave Willock as Pilot (uncredited)

Joe Gilbert as Newsreel Cameraman (uncredited)